Friday, November 21, 2008

Chromosome Arrangement Inside Nucleus

Visualization of a modeled human nuclear genome according to the SCD model. In a, the "initial" configuration with the 46 "start cylinders" is shown. Here, the 1 Mbp domains were placed side by side within the start cylinders. (b) Relaxed interphase state after 400,000 Monte Carlo steps. The simulated CTs are visualized in 24 pseudocolors. The visualization was done using the Persistence of Vision Ray-Tracer Pov-Ray (POV-Team, Williamstown, Victoria, Australia). Bar, 5 ┬Ám.


G. Kreth, J. Finsterle, J. von Hase, M. Cremer and C. Cremer
Radial Arrangement of Chromosome Territories in Human Cell Nuclei: A Computer Model Approach Based on Gene Density Indicates a Probabilistic Global Positioning Code
Biophys. J. 2004 86: 2803-2812